Some people prefer Facebook more than websites. In the interests of broader public education, a new Lewy Body Dementia page on Facebook has been launched. Whenever I see something that is significant or valuable to the community, it will be posted there. Every post will be personally analyzed to ensure a higher level of trust and legitimacy and will have a summary or comment to allow very quick scanning, to keep the page easy to search, and to save you time in case a specific article is not going to be what you’re looking for.

Below, you’ll find the five most recent posts, which is automatically updated. There is a great deal of online content that is specifically intended to manipulate, provoke, deceive or get visibility for the wrong reasons. Finding, reading, researching, and analyzing each article takes significant time, and I want only the best and most trustworthy to appear.

Click the Facebook page and “like” it to see most of them on your Facebook timeline as they are added. I will ensure that this is never overwhelming, off-topic, or insensitive.
One key reason that accurate diagnosis, and even more so, treatment are so challenging is because of the ultra complex, constantly changing interplay of pathologies in the brain. As the neurologist says in this article, he finds a single underlying cause is virtually never the issue but that 80-90% are combinations of different root causes.
In this case, repeated head trauma was believed to have led to CTE, and the cognitive and behavioural challenges. At autopsy, CTE was present, but so was Alzheimer’s Disease, LBD, and a fourth culprit, a protein TDP-43.
As the causes shifted in dominance, it would be nearly impossible to stabilize any medication treatment. This is something anyone touched by dementia will likely contend with.
Strength to all! Timothy Hudson
LBD Diagnostic Challenges: This is a fascinating, if rather complex, recounting of the process of diagnosis of an individual. Like very many people, the diagnosis was far from clear, nor linear. And it provides insights into why it's so difficult to get a proper diagnosis, and also serves as a cautionary tale about making sure a diagnosis is, in fact, correct. Because in this case, it appears to have been wrong.
From the article, "Dementia with Lewy bodies can be challenging to diagnose correctly and is subsequently underdiagnosed. Neuroimaging is often used to aid clinicians make the diagnosis. Here the authors describe a case where a patient was misdiagnosed with the condition due to their antidepressant therapy influencing their scan result."
As biomarkers for LBD emerge, and improved diagnostic tests add to the clinical features, I expect clarity of diagnoses will improve. Here's to that. And soon!
Strength to all. Timothy Hudson
Having LBD as the single neural pathology results in a much faster decline according to new research (compared to Alzheimer's Disease (AD), or a combination of Alzheimer's plus LBD). The sample study was small, but the findings appear significant, and suggest a 2.7x faster decline for a person with LBD vs a person with AD.
An interesting result, indeed, but I'd like a bigger sample size, and more focus also on the LBD+AD group, since I suspect that mixed dementias, such as this combination, or one of these with vascular dementia, or fronto-temporal dementia are far more common than diagnosis would indicate.
Strength to all. Timothy Hudson
Lewy Science: Newly developed "tracer" substance can be used to image mis-folded Alpha-Synuclien proteins (Lewy Bodies) in a LIVE brain, using a non-invasive PET Scan. In the study, MSA -- a "synucleinopathy" condition, like Parkinson's Disease (PD) and Lewy Body Dementia (LBD) -- has been differentiated from both PD and LBD using this tracer and scan. This is still being tested, developed, and more research is needed, of course.
- To me, the most exciting potential is to see where the mis-folded proteins are aggregated, both to know which condition is dominant, to provide the most effective treatment (since MSA, PD and LBD are on the same spectrum), but also to ensure that typically used medications that may be detrimental to one condition not be used if it is not needed.
- Thanks to Paula Rice Biever for the initial link.
- Strength to all. Timothy Hudson
Lewy Science: New study appears to show a link between the presence of Lewy Bodies in the brain having a lower incidence of dementia when the person also consumed caffiene.
- The language is a bit unclear for my liking, but it seems to imply that caffiene use, in a person with Lewy Bodies in the brain who has NOT yet developed dementia, may have lowered risk than for people without Lewy bodies present.
- I suspect there are more variables that haven't been accounted for. This seems a bit oversimplifying, and potentially misleading, like saying that red wine consumption leads to a longer life. It doesn't.
- All our family members consumed caffiene, although not excessively. Neuroprotective? Hard to say.
- Strength to all! And with a nice cuppa jo! Timothy Hudson
LBD Medication Update: There’s a new version of Levodopa/Carbidopa now available in the US. The big difference is that it’s easier to split into smaller pieces to better distribute the amount and timing of medication taking, and balance the effects.
- It is the same as Sinemet in its relative proportion of levodopa and carbidopa. It’s primarily easier to split in half or quarter.
- Here’s to more nuanced medications! Strength to all. Timothy Hudson

I am not entirely sold on the idea of Facebook, but I absolutely agree it is critical to get information out to the broader public. If this doesn’t work well, it will be retired. Make sure you join a support group for Lewy Body Dementia — there are options online, by email, phone or in-person.

Strength to all!
Timothy Hudson

Updated September 21, 2018